Agriculture and livestock farming are the main economic activities in Killa Saifullah followed by mining and quarrying. There are no data available about the working population of Killa Saifullah by their economic activity. However, to have some idea of the situation, figures about Zhob district in 1981 are given below. According to the 1981 census, the major economic activity in Zhob district was "Agriculture, forestry, hunting and fishing" followed by "construction" and then by "mining and quarrying". Although livestock farming has not been mentioned in the "Agriculture, forestry, hunting and fishing" sector, it is the second major economic activity in the district.

In Killa Saifullah district agricultural crops are categorised in two types, Rabi and Kharif, according to their cultivation seasons. Rabi crops are sown in winter and harvested in late winter or during early summer. Kharif crops are sown in summer and harvested in late summer or early winter. The major Rabi crops of the district include wheat, barley and cumin. Kharif crops in Killa Saifullah district include potato, tobacco, maize, onion, melons, chillies, jowar and pulses including mash and moong. Vegetables and fodder are cultivated throughout the year. All the fruits are produced in Kharif season. Tomato, almond and apple are the major cash crops. Agricultural labour is predominantly male. However, women are involved in allied activities – like manure collection which subsequently is used as fertiliser – and storage of grains. Women’s labour is usually unpaid. Mostly the farming activities are performed by the land owner himself but tenants are also employed, depending on the size of the land holding.