The hills of the district belong mainly to the Toba Kákar range. In Killa Saifullah sub-division, the principal ranges are the Torghar [Shagána Kotal (2,070 m), Azak (2,557 m), Baliaraghar (2,958 m)]; Spínghar which separates the Khaisor valley from the Zhob valley [Shina-ghára (2,646 m), Shorghar, Spínghar (2,936 m), Yavháshki (2,964 m)]; and the southern hills [Churmaghar (2,113 m)]. The principal hills of Muslim Bagh sub-division include Kand (3,288 m) in the extreme west, which in the north is known as Barsha or Nigánd (2,877 m); Súrghund (3,234 m) in the south-western corner; Marzaghán [Atoka (3,007 m)] in the south; Malkand and Sraghar in the north; the Torghar (2,958 m); Yavháshki (2,964 m) on the western spur of the Spínghar range; Thor (2,827 m), Súrghundi (2,528 m), Sharan (2,608 m) and Sakír (3,086 m).

The main drainage of Killa Saifullah district is carried off from west to east by the Zhob river and several of its tributaries. The Zhob river in its upper reaches, is known as Lahar. The northern slopes of the Torghar range are drained by the Kundar, Wali Murgha and a number of hill torrents which traverse the northern portion of the sub-division. In Killa Saifullah sub-division, the principal tributary is the Toi. In Muslim Bagh sub-division, its principal tributaries are the Kamchughai and Rod Faqirzai from the north and Marzaghan from the south.

The greater part of the district is covered with hills and rocks, intersected on the south by the Zhob valley. The valley is an immense stretch of alluvial plain extending from Kan Mehterzai pass onward to the Gomal river in the form of a crescent. The boundary between Quetta valley and Zhob valley is the dividing line between the Continental Watershed and the Central Asian watershed at Kan Mehterzai pass. The rivers in Quetta valley drain into Central Asian watershed. Zhob river drains into the Indus via Gomal river. Numerous small valleys run up from either side of the great Zhob valley into the hills. Among these hills Sharan and Khaisoro valleys are situated. A considerable part of the soil in these valleys consist of virgin land. Pasture lands are frequently found almost everywhere in the district. Killa Saifullah is at an elevation of 1,550 meter above sea level (masl), Muslim Bagh at 1,795 masl and Kan Mehterzai at 2,170 masl.